Entrapped Transient Chloroform Solvates of Bilastine

نویسندگان

چکیده

The knowledge about the solid forms landscape of Bilastine (BL) has been extended. crystal structures two anhydrous have determined, and relative thermodynamic stability among three known polymorphs established. Moreover, chloroform solvates with variable stoichiometry identified characterized, showing that S3CHCl3-H2O SCHCl3 can be classified as transient which transform into new solvate SCHCl3-H2O when removed from mother liquor. determination their combined single crystal/synchrotron X-ray powder diffraction data allowed complete characterization these solvates, being them heterosolvates (S3CHCl3-H2O SCHCl3-H2O) a monosolvate. temperature dependent interrelation pathways BL studied.

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ژورنال

عنوان ژورنال: Crystals

سال: 2021

ISSN: ['2073-4352']

DOI: https://doi.org/10.3390/cryst11040342